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Sequence of the N2 neuraminidase from influenza virus A/NT/60/68

Identifieur interne : 002654 ( Main/Exploration ); précédent : 002653; suivant : 002655

Sequence of the N2 neuraminidase from influenza virus A/NT/60/68

Auteurs : D. R. Bentley [Royaume-Uni] ; G. G. Brownlee [Royaume-Uni]

Source :

RBID : ISTEX:6F7A406BF2C3E2E365D8B7F4D4DAD5E78B43E736

Abstract

The complete sequence of the neuraminidase gene of influenza virus A/NT/60/68 (N2 subtype) was determined following.cloning of full length commplementary DNA into pBR322. Comparison of the predicted amino acid squence with a closely related neuraminidase from A/Udron/72 suggests that point mutations over an extensive region of the primary sequence can contribute to antigenic drift, although the region between amino acid residues 308 and 371 may be particularly significant.

Url:
DOI: 10.1093/nar/10.16.5033


Affiliations:


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